Cognitive bias in rats is not influenced by oxytocin

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dc.contributor.authorWilliams, Keith L
dc.date.accessioned2016-10-27T16:30:15Z
dc.date.available2016-10-27T16:30:15Z
dc.date.issued2016-10-27
dc.description.abstractThe effect of oxytocin on cognitive bias was investigated in rats in a modified conditioned place preference paradigm. Fifteen male rats were trained to discriminate between two different cue combinations, one paired with palatable foods (reward training), and the other paired with unpalatable food (aversive training). Next, their reactions to two ambiguous cue combinations were evaluated and their latency to contact the goal pot recorded. Rats were injected with either oxytocin (OT) or saline with the prediction that rats administered OT would display a shorter average latency to approach on ambiguous trials. There was no significant difference between latencies to approach on ambiguous trials compared to reward trials, but the rats were significantly slower on the aversive compared to the ambiguous conditions. Oxytocin did not affect approach time; however, it was unclear, after follow-up testing, whether the OT doses tested were sufficient to produce the desired effects on cognitive bias. Future research should consider this possibility.en_US
dc.identifier.urihttp://hdl.handle.net/10323/4355
dc.language.isoen_USen_US
dc.subjectCognitive biasen_US
dc.subjectApproach latencyen_US
dc.subjectOxytocinen_US
dc.subjectRatsen_US
dc.subjectPlace preferenceen_US
dc.subjectAmbiguous cueen_US
dc.titleCognitive bias in rats is not influenced by oxytocinen_US
dc.typeArticleen_US

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