OUR@Oakland

OUR@Oakland is Oakland University's institutional repository maintained by the University Libraries. The aim of OUR@Oakland is to collect, organize, and showcase the scholarship, creative work, and archival and special collections created by or affiliated with the Oakland University community.

Communities in DSpace

Select a community to browse its collections.

Now showing 1 - 9 of 9

Academic Departments & Support Units
Material related to administrative and teaching activities of the university's academic departments and support units
Association for Interdisciplinary Studies
Publications created by the Association for Interdisciplinary Studies (formerly Association for Integrative Studies)
Faculty Scholarship
Scholarship produced by OU faculty, including publications, presentations, and research data
Meadow Brook Music Festival
Programs from performances and events presented at the Meadow Brook Music Festival, beginning in the summer of 1964
Oakland University Archives and Special Collections
Historic university materials documenting the foundation and operations of the university and its operations, and collections devoted to specific subjects
Oakland University Art Gallery
Catalogs from various exhibitions presented at the Oakland University Art Gallery
The Oakland Press
Digitized collections of The Oakland Press newspaper and its predecessors (specifically The Pontiac Press)
Theses and Dissertations
Theses and dissertations by Oakland University students, searchable by discipline
Undergraduate Student Scholarship
Scholarship developed by Oakland University undergraduate students working in various disciplines

Recent Submissions

Item

Detecting Behavioral Changes in an Autism Mouse Model after Treatment with Ergothioneine

(2024-12-10) Carpenter, Morgan R.; Pillivant, Dylan; Liu, Zijuan; Stamatovski, Daniel

Autism Spectrum Disorder (ASD) is a neurological disorder that can impair developmental, behavioral, and social skills. Although there are currently no curative remedies authorized for the treatment of autism spectrum disorder, certain dietary supplements may act as a form of therapy for some of the atypical behaviors associated with this diagnosis. Ergothioneine (ET) is an amino acid derivative known for its antioxidant properties and its ability to enhance neurological function. Here we utilized ET supplementation to examine the potential benefits it may have on autism phenotypes. A BTBR autistic mouse model was used to test the effects of ET treatment followed by behavioral examination. Quantitative analyses of behavioral changes observed between the treatment group along with controls were performed to determine if ET could improve autism-like behaviors. The long-term goal of this study is to establish the possible application of a safe ET supplementation to ameliorate autistic manifestations in ASD children.