Biomedical Sciences
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PRECLINICAL STUDIES: TREATMENT OF MULTIPLE SCLEROSIS AND RETINAL DEGENERATIVE DISEASE USING STEM CELLS
(2021-11-15)Pluripotent stem cells (PSCs) isolated from an embryo or generated by ectopic expression of transcription factors can self-renew indefinitely and differentiate into all cell types found in the body. PSCs have the highest ... -
PHOSPHORYLATION PATTERNS, AGGREGATION PROPENSITIES, AND MORPHOLOGICAL STUDIES OF THE VARIOUS TAU PROTEIN ISOFORMS
(2022-03-25)Tau protein is a microtubule-binding protein as well as a biomarker of neurodegeneration. Its core function is to stabilize microtubules for proper neuronal communication. When hyperphosphorylated, it detaches itself from ... -
MULTI-RESOLUTION STUDY OF TOPOGRAPHICAL AND ZONAL PROPERTIES OF OSTEOARTHRITIS IN ARTICULAR CARTILAGE USING MICROSCOPIC MRI AND POLARIZED LIGHT MICROSCOPY
(2022-03-22)Articular cartilage is a thin layer of connective tissue found in diarthrodial joints that overlay the opposing ends of bones and acts as lubricating surfaces to distribute stress and reduce friction with the help of ... -
THE ROLE OF CD49f - INTEGRIN α6- IN HUMAN STEM CELL BIOLOGY
(2021-11-15)Owing to the intrinsic capability for unlimited self-renewal and the ability to make all the cells in the body, pluripotent stem cells (PSC) are an ideal candidate to be used as starting material for cell therapies. The ...