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Oakland University - News Archive - Eye research program pays off for students
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(Tuesday, July 13, 2004)Tj
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(Eye research program pays off for students)Tj
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(Kenneth Mitton, assistant professor of biomedical sciences, challenges h\
is student researchers in the Summer)Tj
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(Undergraduate Research Program in Eye Research \(SUPER\) \226 and they\222\
re finding their hard work is paying big)Tj
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(rewards.)Tj
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(Former student researchers are being accepted to prestigious graduate pr\
ograms and this spring grabbed national)Tj
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(awards at the Association for Research in Vision and Ophthalmology \(ARV\
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(\223Students often continue to do their fourth year independent research\
course during the winter and fall terms,\224 Mitton)Tj
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(said. \223Research students are encouraged to participate in the communi\
cation of results at scientific meetings such as)Tj
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(ARVO. Submissions of abstracts to this meeting are peer reviewed and rul\
es for acceptance are fairly strict.\224)Tj
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(Nearly 10,000 researchers and clinicians attended the ARVO meeting, wher\
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(including two OU undergraduate students, presented three accepted abstra\
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(As OU undergraduate biology students, Danielle Doyle )Tj
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(\(CAS \22204\))Tj
( and Janice Loffreda-Wren \(CAS \22203\) earned an)Tj
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(ARVO-National Eye Institute travel meeting award for young investigators\
for the laboratory\222s abstract, \223Economical)Tj
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(Q-PCR Kits for Mouse Retinal Gene Expression: ERI Eye Gene Matched Prime\
r cDNA Kits.\224)Tj
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(Also at the conference, Mitton presented with biology major Jenae Johnst\
on, CAS \22204, and Anand Swaroop,)Tj
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(University of Michigan professor, an abstract, \223Fiz1: A Novel Zinc-fi\
nger Protein Binds the NRL Transcription Factor)Tj
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(Using Internal Domains Different from its RTK-Binding Domains.\224)Tj
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( )Tj
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(Mitton is researching human retinal diseases and how genes interact. Wit\
h his undergraduate student researchers, he)Tj
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(is exploring one of the first known repressors that can affect the expre\
ssion of photoreceptor specific genes. Mitton\222s)Tj
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(laboratory is one of only few in the world using a molecular-biology tec\
hnique, called the yeast two-hybrid trap, to)Tj
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(discover previously unknown interactions between transcription factors t\
hat control rod-specific genes.)Tj
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(Mitton discovered four protein interactions involving transcription fact\
ors that regulate rhodopsin gene expression.)Tj
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(Rhodopsin is the fundamental light-detecting protein of rod-photorecepto\
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(repressor protein \(called Fiz1\) that is the central focus of the lab.)Tj
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(In the laboratory, Mitton provides students with real-world research exp\
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(\224Students are doing lab exercises just as complicated as what they\222\
d do in a graduate lab,\224 Mitton said. \223I\222m giving)Tj
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(This research experience benefits those students who apply to graduate s\
chool. Loffreda-Wren will be attending the)Tj
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(University of Michigan this fall as a graduate student in biomedical sci\
ences affiliated with the Department of Human)Tj
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(Genetics.)Tj
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( )Tj
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(\223My experience at the ERI was a major factor in my acceptance into th\
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(During my interview process)Tj
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(at both the University of Michigan and University of Virginia, where I w\
as also accepted, many professors told me that)Tj
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(they were looking for someone like me because of my research experience,\
\224 Loffreda-Wren said. \223Grad schools want)Tj
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(to know that their future Ph.D. candidates can be active researchers and\
there is no better way to prove that than by)Tj
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(actually doing research at the undergrad level.\224)Tj
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(Biology major Afreen Siddiqui, CAS \22203, and a 2002 SUPER student, was\
accepted into the Ph.D. program in cancer)Tj
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(research at the Karmanos Cancer Institute at Wayne State University. The\
program admits only six new students each)Tj
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